Information that covers MCF in ruminants.

“Lympho” and “Cheesy gland” are common names used by livestock owners and veterinarians for caseous lymphadenitis (CL), a bacterial disease that affects small ruminants such as sheep and goats. A worldwide problem, CL is caused by Corynebacterium pseudotuberculosis and once endemic on a farm is difficult to eradicate.  Primarily a disease of economic importance in […]

Q: What is G6S, and why should I test for it?Caprine mucopolysaccharidosis-iiid is a lysosomal storage disorder, caused by a genetic mutation (a point mutation) which results in a defective G6S (N-Acetylglucosamine-6-sulfatase) enzyme. The only method for testing for this genetic defect is with a DNA test identifying the causative point mutation.  Goats should be […]

The Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) offers digital toxicology to account-holding clients. Digital toxicology provides evaluation of photos taken with smart phones, or other digital cameras, and an official report identifying items photographed (where possible) including an attachment with labeled photos for later reference – an advantage over shipping items to the laboratory […]

The Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) Analytical Chemistry Section has the ability to offer toxicology and drug testing services to livestock producers and practitioners. The lab offers a variety of tests to aid in diagnosing many conditions of both toxic and nutritional origin. Our highly trained and qualified personnel use state-of-the-art analytical techniques […]

Fumonisin B1 is the most prevalent of several fumonisin mycotoxins (B1, B2, B3) produced by Fusarium molds in corn. Corn contamination can occur at very high levels when permissive environmental conditions coincide with vulnerable points in corn kernel production. Equine Leukoencephalomalacia (ELEM) Horses and other equids, as well as rabbits, are the most fumonisin-sensitive species. […]

Prior to diagnostic testing, it’s important to determine what factors would lead to the most comprehensive assessment of an animal’s condition. Each case must be evaluated individually in order to establish the most practical diagnostic testing route.  Collection Guidelines What is an ideal serum sample? Since most serologic testing utilizes serum, blood should be collected […]

The Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) performs numerous tests using serum. Proper collection, preparation, and packaging for transportation is imperative to obtaining a quality serum sample. Serum samples that arrive at TVMDL which are hemolyzed and/or lipemic may not be acceptable for testing. Accurate results start with an ideal sample. Ideal Sample Clear […]

Hundreds of samples arrive daily at the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) for testing. Testing accuracy often depends on submission of the proper specimen for the assay, particularly for molecular diagnostics.  To ensure the appropriate sample is submitted for molecular diagnostics at TVMDL, please consult the website for specific details associated with the […]

Hundreds of samples arrive daily at the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) for testing. Testing accuracy often depends on the submission of the proper specimen for the assay, particularly for molecular diagnostics. With the proper sample, we can perform the assay and provide the most timely and accurate results without delay.  While results […]

A forensic or legal necropsy as defined by the purposes of the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) is a necropsy done to attempt to determine the cause of death in cases where the death is known or suspected to be non-natural, there are suspicious circumstances, or there is evidence of foul play. They […]

Click to Skip: Autolysis | Cautery Artifact | Freezing Artifact | Crush Artifact | Sponge Artifact Pathologic artifacts are any structures or features that are not normally present in the living animal. Some are minor, easy to distinguish from normal or diseased tissue, and/or do not interfere with the pathologists’ ability to provide an accurate […]

The body of a 3-month-old goat was submitted to the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) in College Station. This goat had been purchased 3 weeks prior. The goat was euthanized due to sudden onset of neurological signs and was also noted to have a crusty lesion on the lip. Gross necropsy confirmed there […]

Click to Skip Tips for Collecting Needle and Core Bone Biopsy | Tips for Submitting and Entire Leg | Clinical History Submitting samples of bone for histopathological analysis is essential to definitively diagnose most primary bone diseases (e.g., osteosarcoma). However, collecting representative bone biopsy specimens and their histopathological interpretations presents several challenges for the clinician […]

Dermatology cases are one of the most common types of cases seen by general practitioners. A crucial diagnostic tool in these cases is the skin biopsy. They are indicated in cases that do not respond to normal therapy, pustular, or ulcerative disease, and suspected neoplasia.  Before Taking a Skin Biopsy Prior treatment should also be […]

Diagnosing animal diseases frequently requires a veterinarian or a technician to collect specimens in the field. This can be difficult without having the right tools on hand. For these occasions, the Texas A&M Veterinary Medical Diagnostic Laboratory suggests assembling a necropsy field kit. The kit should include the following tools and materials, all of which […]

Click to Skip: Bone Marrow Aspirate Procedure | Bone Marrow Core Biopsy Procedure Bone marrow testing is used to diagnose and monitor bone marrow diseases and CBC abnormalities. Full evaluation of bone marrow requires a CBC the day of the bone marrow collection, bone marrow aspiration, and a bone marrow core biopsy.  Indications for bone […]

Although there have been substantial advances in benchtop hematology instrumentation for veterinary species, manual evaluation of a blood smear remains a vital part of a complete blood count (CBC). At the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL), all CBCs include manual blood smear examination by a highly skilled clinical pathology technician, a clinical pathologist, […]

The Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) offers digital cytology to account-holding clients. Digital cytology provides rapid evaluation of photos taken with microscope cameras or smart phones. This service provides an official report and cytologic interpretation, typically within one hour of submission (during business hours). To enhance this service, submission of glass slides for […]

This assay utilizes rtPCR technology on E. coli isolates recovered from ruminant samples. Samples are recovered by the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) bacteriology section to further characterize the potential of the isolate to be participating in the current patient clinical syndrome.  The significance of the detected genes should be interpreted with the […]

The collection of hair samples should be undertaken by a competent individual within a secure, contamination-free facility. Hair is a strong, stable tissue that is simple to collect, transport, and store. Data suggest hair is as effective a matrix as retinal tissue for detecting beta-adrenergic agonist drugs (i.e. clenbuterol, zilpaterol, ractopamine and albuterol). Please note […]

Anthrax is caused by a gram positive, rod-shaped bacteria called Bacillus anthracis. This is a spore forming bacteria that can persist in dry, alkaline soil of endemic areas such as southwest Texas. Cattle, sheep, goats, deer, and horses are more susceptible to infection than pigs, birds and carnivores, like dogs and cats. In herbivores, anthrax […]

Samples from a one-year-old Boer goat doe were received at the TVMDL for testing.  The doe had displayed neurological signs including unilateral paresis, droopy lip and hypersalivation, torticollis upon stimulation, obtundation, and lateral recumbency.  The goat was also febrile. Clinical differentials included listeriosis, polioencephalomalacia, bacterial meningitis, and rabies virus. Treatment consisted of antibiotics, anti-inflammatory drugs, […]

Polioencephalomalacia “polio” is a syndrome of ruminant animals affecting the central nervous system. Seizures are the most notable sign, progressing quickly to the death of the affected animal without treatment. The underlying cause of the syndrome is a disturbance in thiamine (Vitamin B1) metabolism. Since ruminant animals can assemble B vitamins in their rumens, affected […]

Enterotoxemia, commonly called “overeating disease”, is a common problem in sheep and goats, especially in animals under a year of age. The disease occurs in peracute, acute, and chronic forms. The causative bacterial organism is Clostridium perfringens with types C and D being the most common forms. Type C is said to be seen most commonly in […]

Coccidia are single-celled parasites that are common in many species, including goats. Diagnosis of coccidiosis is most commonly achieved through fecal flotation in specimens from live animals. Characteristic lesions can also be seen at necropsy. This article will highlight a recent case of coccidiosis in a goat kid at the Texas A&M Veterinary Medical Diagnostic […]

An 8-month-old male sheep was purchased out of state at the end of September. The animal was clinically normal until November 1 when it was noted to be having a seizure. The animal could not stand or walk and was observed to be chewing on its rear legs.  The clinical signs progressed until November 4 […]

In reflecting upon yet another major livestock show season in Texas, it is important to keep in mind the possibility of copper toxicity, particularly in sheep and goats. Sheep are particularly sensitive to excess copper in their diets. Although goats are not as sensitive as sheep, they can still become intoxicated with too much copper. It […]

A term sheep fetus was submitted to the Texas A&M Veterinary Diagnostic Laboratory (TVMDL) for a routine necropsy. The fetus had scoliosis. The skull and maxillae were deviated to the left. There was no intact brain tissue in the cranial vault. In place of the brain there was a thin membranous sac filled with reddish […]

In late March, the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) diagnosed senna toxicosis in two separate goat herds, from west and central Texas. In the first case, a 2-month-old goat kid was found suddenly dead along with one other goat kid. A third surviving kid was reported to be clinically ill. Histologically, the heart […]

The Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) recently diagnosed Q (Query) fever in a 3-week, pre-term aborted goat fetus. The clinical history indicated that four nannies on the same premises aborted during the course of 48 hours. All aborted nannies showed no other clinical signs of disease. During an external examination of one of […]

Many Texans rely upon the weather for a variety of reasons. From crops to cattle, Texans are often at the mercy of Mother Nature. Although droughts can have a dire impact on animal health, floods can also contribute to widespread issues among animal owners. Excessive rainfall can contribute to mosquito-borne diseases, toxic plants, dermatologic conditions, […]

Too often the Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) receives samples where there is a concern for rabies testing but the brain tissue submitted is not suitable for testing by the Department of State Health Services (DSHS) in Austin. Usually the problem is an incomplete sample where only half the brain is submitted.  Less commonly, […]