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Cortisol – ACTH Stimulation Profile – Canine 2 Hour (ChL)

Measurement of cortisol at baseline and 2 hour post ACTH stimulation with ACTH gel. Test performed by chemiluminescence.

NameCortisol – ACTH Stimulation Profile – Canine 2 Hour (ChL)
Code1152.W
SectionClinical Pathology
SpeciesCanine
Specimen

0.5 mL serum

Sampling Requirements

According to the 2012 American College of Veterinary Internal Medicine (ACVIM) consensus statement on canine hyperadrenocorticism:--Only the use of synthetic ACTH (Cosyntropin) is recommended, whereas the utilization of compounded ACTH ("gel") is discouraged due to lower purity and lower quality control.--Acceptable doses for Cosyntropin are 5 micrograms/kg or 250 micrograms/dog IV or IM (lower doses than 5 micrograms/kg have never been validated in Cushing dogs), and 2.2 U/kg IM for compounded ACTH.--Using Cosyntropin, the cortisol peak occurs 60 - 90 minutes post injection, with no significant difference between 60 and 90 minutes.--Using compounded ACTH ("gel"), cortisol concentrations are similar across various compounded ACTH products (and to the gold standard Cosyntropin 5 micrograms/kg IV) at 60 minutes post injection, whereas cortisol concentrations vary considerably at later times.--Avoid hemolysis.

Collection Container

Remove from red cells and place sample in an additive free transport tube.

Packing Instructions

Label all samples. Ship overnight on cold packs.

Special Instructions

None

Price$26.00
Schedule
Lab Schedule Turnaround time
College Station Monday, Tuesday, Wednesday, Thursday, Friday1 day

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